Messi latches onto an Iniesta through ball, controls it on his chest and tries to delicately chip Casillas, but the keeper stays big and blocks the effort.

Messi slips a precise pass into Villa, who touches the ball past Casillas and goes down under contact, but Barcelona’s strong penalty appeal is waved away.

Messi embarks on a mazy dribble through the Real Madrid defence and ends up on the turf clutching his head after an awkward collision with Xabi Alonso’s backside, but quickly recovers.

Messi shows a flash of brilliance, evading a challenge and playing a one-two with Villa before stretching to shoot, but Casillas reacts sharply to palm the effort away.

After Albiol drags down Villa in the box, Messi steps up and calmly sends his penalty past Casillas, giving Barcelona the lead despite the keeper getting close to the shot.

Messi produces a wonderful run and nearly breaks through after a sharp one-two with Villa, but Real Madrid just manage to snuff out the danger.

Messi drives forward and slips the ball across to Villa in the area, but a bobble makes the chance awkward and Villa’s shot goes straight at Casillas.

Barcelona craft a neat move and Iniesta almost threads the perfect pass through for Messi, but Casillas anticipates it brilliantly and gathers before Messi can reach it.

Messi skips past Arbeloa into the Real Madrid box during a frenetic end-to-end spell, helping create a chance that ultimately sees Iniesta slice a half-volley wide.

Chasing a ball that is running out of play, Messi vents his frustration by blasting it into the crowd, provoking an angry reaction as home fans hurl flags back towards him.